http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107525935-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90209 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57488 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y106-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2016-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107525935-B |
titleOfInvention | Methods and compositions for targeted two-dimensional immunoblot analysis for early cancer detection and cancer diagnosis up to ten years before clinical symptoms of malignant disease |
abstract | The present invention includes a method for detecting benign to malignant transformation of cancer in a subject comprising the steps of: collecting a sample from the subject prior to electrophoretic protein separation; activating electrophoretically separated ENOX2 transcriptional variants using an ENOX2 electron donor and detecting the presence of one or more activated ENOX2 transcript variants using a pan-ENOX2-detectable binding reagent, wherein the presence of the one or more activated ENOX2 transcript variants in the sample is indicative of malignant transformation of the cancer, Thereby a 10- to 100-fold increase in the detection sensitivity of one or more activated ENOX2 transcript variants is obtained when compared to the equivalent non-activated ENOX2 transcript variant. |
priorityDate | 2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 851.