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filingDate 2017-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84efe7ef1b3cb8262f60a9d6db1aac84
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publicationDate 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107523646-A
titleOfInvention Method based on nucleic acid mass-spectrometric technique detection early diagnosing mammary cancer related gene
abstract The invention belongs to field of gene detection, and in particular to a kind of method based on nucleic acid mass-spectrometric technique detection early diagnosing mammary cancer related gene.The present invention provides the combined detection method of 15 mutational sites related to breast cancer of 4 genes and 18 breast cancer susceptibility SNP sites of 10 genes, and Genotyping detection is carried out to the SNP site of breast cancer susceptibility gene and the gene mutation site related to breast cancer using SequenomMassARRAYSNP genotypings technology.This method for breast cancer early screening is more accurate, technique reproducible is good, cost-effective;The SNP detections being sequenced compared to TaqMan PCR and two generation platforms, with flexible design, accuracy is high, detection site sample size is big, low cost and other advantages, can carry out hundreds of to thousands of parts of pattern detections to dozens of SNP site simultaneously.
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