http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107522627-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-04 |
| filingDate | 2017-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107522627-B |
| titleOfInvention | Preparation method of 5-aminolevulinic acid hydrochloride |
| abstract | the invention relates to a preparation method of 5-aminolevulinic acid hydrochloride, belonging to the technical field of synthesis of drug intermediates. In order to solve the problem of large pollution of the existing route, the method for preparing the 5-aminolevulinic acid hydrochloride is characterized by comprising the steps of reacting benzoylglycine and succinic anhydride in the presence of organic base and DMAP (dimethyl formamide P) to obtain benzoylaminolevulinic acid; benzoylaminolevulinic acid is subjected to a hydrolysis reaction in the presence of hydrochloric acid to give 5-aminolevulinic acid hydrochloride. The synthesis method has the advantages of short reaction route, convenient raw material source, low cost, simple and convenient reaction operation, less pollution and the like, and has the effects of high product yield and high purity. |
| priorityDate | 2017-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.