http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107513092-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J17-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2017-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107513092-B |
| titleOfInvention | Malonyl ginsenoside Rb1Preparation method and medical application thereof |
| abstract | The invention provides malonyl ginsenoside Rb 1 The preparation method comprises the following steps: chopping fresh Ginseng radix or radix Panacis Quinquefolii, performing enzymolysis with laccase, performing ultrasonic extraction, recovering solvent from the extractive solution at 40 deg.C under reduced pressure, concentrating to obtain water solution, separating with NKA-12 adsorbent resin, and performing gradient elution with ethanol to obtain malonyl ginsenoside extract. Separating malonyl ginsenoside extract by ODS pressurized column chromatography, and gradient eluting with ethanol or acetonitrile and buffer salt solution. Detecting with thin layer plate chromatography, and detecting whether the product contains malonyl ginsenoside Rb 1 Concentrating the eluate, recovering solvent, desalting the concentrated solution with dextran gel, and recrystallizing with ethanol to obtain malonyl ginsenoside Rb 1 And (5) purifying. The pharmacodynamic and pharmacological research shows that the malonyl ginsenoside Rb 1 Has obvious treatment effect on type 2 diabetes and nephropathy complicated with the type 2 diabetes, can be applied to the preparation of health food or medicines, is safe and reliable, has no toxic or side effect, and has good medicinal prospect. |
| priorityDate | 2017-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 148.