http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107513031-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-27 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27 |
| filingDate | 2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107513031-B |
| titleOfInvention | A kind of preparation method of 2-oxo-1-pyrrolidine chiral derivative |
| abstract | The present invention provides a method for preparing a 2-oxo-1-pyrrolidine chiral derivative, specifically, comprising the following steps: a) a compound of formula III and a compound of formula II or a salt thereof undergo a "one-pot" reaction in the presence of a solvent method" reaction, the "one-pot method" reaction sequentially includes condensation reaction in the presence of a base, reduction reaction and ring-closure reaction in the presence of an acid to obtain the compound of formula VI; b) the compound of formula VI in the presence of a solvent and a catalyst Then, the compound of formula I is obtained by reduction reaction. The invention has the advantages of simple process route operation, low cost, easy industrial production and the like. |
| priorityDate | 2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.