http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107501299-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate | 2017-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107501299-B |
| titleOfInvention | Simultaneously [3,2-a] pyrimidine -2- carboxamides derivatives and the application of 5,7- diphenyl -5H- thiazole |
| abstract | The invention discloses 3- methyl -5,7- diphenyl -5H- thiazole simultaneously [3,2-a] pyrimidine -2- carboxamides derivatives or its pharmaceutically acceptable hydrates, salt, including its stereoisomer or tautomer of general formula I, wherein the R in Formulas I 1 And R 2 It is independently hydrogen, methyl, halogen, hydroxyl, methoxyl group, acetyl group, propiono, nitro or alkoxy；R 3 And R 4 Independent alkyl or R selected from C1-C6 3 And R 4 Pyrrole radicals, piperidyl, morpholinyl, N methyl piperazine, N- (4- bromophenyl piperazine) are formed together with the nitrogen-atoms being connected with them.Simultaneously [3,2-a] pyrimidine -2- carboxamides derivatives are as vascular endothelial growth factor receptor tyrosine kinase inhibitor for 3- methyl -5,7- diphenyl -5H- thiazole of the invention, for treating and preventing the purposes of various cancers. |
| priorityDate | 2017-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.