http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107501267-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 |
filingDate | 2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107501267-B |
titleOfInvention | A kind of method of asymmetry allyl aminating reaction synthesis of chiral acyclonucleosides analog |
abstract | The invention discloses a kind of methods of asymmetric allyl aminating reaction synthesis of chiral acyclonucleosides analog, belong to technical field of organic synthesis.Reaction dissolvent, purine compound 1, additive, SKP biphosphine ligand and Metal Palladium are mixed, MBH adduct 2 is subsequently added into, acyclonucleosides 3 is obtained after insulation reaction.The present invention is easy to get with raw material, it is easy to operate, reaction condition is mild, reacts the chiral branch N- allyated products that excellent regioselectivity (up to 99%B/L) and excellent corresponding selection (up to 99%ee) are waited until in can achieve. |
priorityDate | 2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.