http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107496901-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 |
| filingDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107496901-B |
| titleOfInvention | Cell autophagy inhibitor and preparation method and application thereof |
| abstract | The invention discloses a cell autophagy inhibitor taking rubiaceae-type cyclopeptide as an effective component, which is particularly used for inhibiting KRAS mutation, particularly KRAS-dependent tumor cell protective autophagy and promoting tumor cell apoptosis; the inhibitor is preferably a nano micelle injection, and can be applied to preparation of medicines for treating and preventing KRAS-related cancers including colon cancer, rectal cancer, lung cancer and pancreatic cancer. The cell autophagy inhibitor can effectively inhibit tumor cell protective autophagy, has wide sources of active ingredients of rubiaceae cyclopeptides, mature extraction process and diversified dosage forms and medication modes, can be applied to treatment and prevention of KRAS-related cancers, and has wide clinical application prospect. |
| priorityDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.