| abstract |
The invention discloses a pulse-release traditional Chinese medicine preparation for treating cardiovascular diseases and a preparation method thereof. The preparation is a tablet or a plug capsule, wherein the drug-containing core of the tablet and the drug-containing granules of the plug capsule both include Active ingredients in the following weight ratio: Radix Paeoniae Rubra Extract 10‑20: Rhizoma Chuanxiong Extract 10‑20: Panax notoginseng Extract 30‑100: Borneol 1‑3. The invention uses Radix Paeoniae Rubra extract, Rhizoma Chuanxiong extract, Panax notoginseng extract, borneol, etc. as active ingredients, has the effects of benefiting blood, dispelling blood stasis, relieving pain, resuscitating one's ideas, and promoting Qi, and can effectively treat cardiovascular diseases. At the same time, the drug is made into a pulse-release drug preparation in the present invention, which can release the drug regularly and quantitatively according to the patient's circadian rhythm and the time of disease onset. The drug release in vivo and in vitro has a good correlation, and it is the most ideal oral time-delivery system so far. One, it can significantly improve the curative effect, reduce the frequency of medication and increase patient compliance. |