http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107475312-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-66 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-07 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate | 2017-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107475312-B |
| titleOfInvention | Method for effectively producing vitamin K2 by improving cell membrane permeability |
| abstract | The invention discloses a method for effectively producing vitamin K2 by improving cell membrane permeability, which comprises the following steps: (1) inoculating a vitamin K2 production strain into a slant culture medium for activation; (2) inoculating the activated strain into a seed culture medium added with a non-ionic surfactant for culture; (3) continuously inoculating the obtained culture solution into a seed culture medium added with a non-ionic surfactant for culture; (4) inoculating the culture solution into a fermentation culture medium, culturing at 100-700rpm at 0.5-5vvm for 144-240 h; when the fermentation time is 0-72h, adding a nonionic surfactant, performing insertion low-power ultrasonic treatment at intervals, and sampling at regular time to detect the cell and vitamin K2 concentrations. The invention has the advantages that: provides a simple, effective and economic fermentation process, effectively improves the concentration of vitamin K2, improves the production efficiency and reduces the production cost. |
| priorityDate | 2017-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.