http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107474135-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-46 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate | 2017-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107474135-B |
titleOfInvention | anti-PD-1 nano antibody PD-1/Nb20 and preparation method and application thereof |
abstract | The invention discloses an anti-PD-1 nano antibody PD-1/Nb20 and a preparation method and application thereof. The nano antibody provided by the invention comprises a determinant complementary region and a framework region; the determinant complementary region of the nanobody consists of CDR1, CDR2 and CDR 3; through the nano antibody nucleotide sequence and the host cell disclosed by the invention, the nano antibody can be efficiently expressed in escherichia coli, and is applied to the research and development of PD-1 molecular detection reagents, the preparation of tumor inhibitors or tumor cell inhibitors and the preparation of medicines for inhibiting PD-1 activity and promoting T cell proliferation. |
priorityDate | 2017-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 182.