http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107459532-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6539 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 |
filingDate | 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107459532-B |
titleOfInvention | A kind of new Anti-cancer medicament intermediate |
abstract | The invention discloses a kind of new Anti-cancer medicament intermediates; compound of formula III (IIIa or IIIb); using 2- acetyl group -4- formic acid esters thiazolium compounds as raw material, by halogenating reaction, then reacts and be made with triphenylphosphine, Trimethyl phosphite, triethyl phosphite etc..Formula III compound may further be used to prepare Anti-cancer medicament intermediate, such as and isobutylaldehyde, by Wittig reaction or Wittig-Horner react, obtain compound of formula I.Entire technique is new process, can not only reduce the prices of raw materials, and reaction condition is also mild, and the three wastes of generation are few, is easy industrial applications. |
priorityDate | 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.