http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107445798-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C31-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C321-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-34 |
| filingDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107445798-B |
| titleOfInvention | Synthetic method of alpha, alpha-dideuteroalcohol compound |
| abstract | The invention belongs to the field of organic synthesis, and relates to a synthesis method of an alpha, alpha-dideuterol compound, which is selected from the following single electron transfer reaction methods comprising alkali metal media: ester compounds shown in a general formula (1) or amide compounds shown in a general formula (3) react with an alkali metal reagent and deuterated alcohol in an organic solvent to generate alpha, alpha-dideuterio shown in a general formula (4)Substituted alcohol compounds or lactone compounds shown in the general formula (2) react with alkali metal reagents and deuterols in organic solvents to generate alpha, alpha-dideuterol compounds shown in the general formula (5), the synthesis method of the alpha, alpha-dideuteroalcohol compound has the advantages of high yield, safe and simple operation, easily obtained raw materials, short reaction time, no transition metal electron donor reagent used in the preparation process, and expensive and flammable metal deuteride (such as NaBD) 4 ，LiAlD 4 Etc.) and combustible gases, and no harmful by-products are produced. |
| priorityDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.