http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107434823-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 |
| filingDate | 2017-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107434823-B |
| titleOfInvention | A kind of purification method of oritavancin intermediate A82846B |
| abstract | The invention provides a purification method of oritavancin intermediate A82846B. Specifically, the method includes: loading the A82846B fermentation broth onto an ion-exchange resin chromatography column, elution and separation to obtain a first eluent; and then loading the first eluent onto silica gel C18 or polyphenylene In the reversed-phase chromatography column with ethylene polymer as filler, the impurities are eluted first, and then the sample is eluted to collect the second eluent, and the purity of the obtained A82846B is greater than 80%. The method of the present invention can not only ensure the quality of the product, but also is suitable for the expanded commercialization market. Meanwhile, the present invention also provides a method for preparing oritavancin intermediate A82846B salt, and a method for synthesizing oritavancin by utilizing A82846B salt. |
| priorityDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.