| abstract |
The invention provides a kind of cationic polymer/TDNs to carry medicine compound, and its preparation method comprises the following steps：PEI solution and TDNs solution are mixed according to N/P=0.2 7.5 ratio, are incubated 15 30min at room temperature, is made.This method is mixed the PEI solution of certain concentration with the TDNs of certain concentration according to specific N/P, its gained carries the biocompatibility that medicine compound can effectively improve cation, it can also avoid TDNs from being degraded by DNA enzymatic simultaneously, promote it to enter intracellular, so as to play the purpose for effectively carrying medicine. |