http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107432860-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 |
filingDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107432860-B |
titleOfInvention | Preparation method of levo-oxiracetam freeze-dried powder |
abstract | The invention discloses a preparation method of levo-oxiracetam freeze-dried powder; the levo-oxiracetam freeze-dried powder contains the following raw and auxiliary materials in percentage by weight: 50% -59% of levo-oxiracetam, 20% -25% of L-serine, 10% -17% of mannitol, 5% -7% of sodium glutamate, 5% -10% of sodium bisulfite and 0.1% -0.5% of phenol; the levo-oxiracetam freeze-dried powder is prepared by the steps of concentrated preparation, diluted preparation, freeze drying and capping. The invention utilizes the specific excipient combination and is matched with the specific freeze-drying technology, so that the prepared levo-oxiracetam freeze-dried powder has a fixed shape, the phenomenon of bottle spraying is avoided in the freeze-drying process, the product uniformity is good, the upper layer and the lower layer are consistent in character, the antibacterial property is strong, the product is qualified through sterile inspection, the product stability is good, and the insoluble particles are obviously reduced. |
priorityDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.