http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107430122-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54346 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate | 2016-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107430122-B |
| titleOfInvention | The method and standard sample for being used to prepare the standard sample of the protein condensation product for detecting protein Misfolding illness are used with it |
| abstract | The present invention relates to a kind of standard samples for being used to prepare the protein condensation product for detecting protein Misfolding illness, band has the following steps: A) inorganic nanoparticles of the condensation product size with protein Misfolding illness are provided, B free amino or free carboxyl) are formed at nano grain surface, (with for make nano grain surface functionalization at aminofunctional or carboxy-functionalized nano particle) C) i) maleimide-interval base-carboxylic acid is integrated to step B) and in free amine group in, or ii) the free carboxyl in step B) is changed into NHS ester, D) the monomer i) of protein condensation product is integrated at maleimide-interval base-carboxylic acid via in the sulfhydryl of monomer free end, or ii) be integrated at NHS ester via the amino of the free end in monomer.Object of the invention is a kind of standard sample and its use in the situation for the protein condensation product that detection occurs in the case where protein Misfolding illness. |
| priorityDate | 2015-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.