Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-557 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-14 |
filingDate |
2016-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-107427550-B |
titleOfInvention |
cell penetrating antibody |
abstract |
Cell penetrating conjugates are provided herein. The conjugate includes a non-cell-penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone by a non-covalent linker, wherein the non-covalent linker includes a biotin-binding structure domains and biotin domains wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of non-cell penetrating proteins. Compositions and kits comprising the conjugates are also provided. |
priorityDate |
2015-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |