abstract |
A hot melt extruded solid dispersion composition, a method of preparing the same and the use of the composition in the manufacture of a medicament for the prevention and/or treatment of a disease caused by plasmodium. The composition comprises, by weight, decoquinate 5-30%, a polymeric carrier material 60-90%, and a surfactant 0-10%. The process for preparing the composition comprises the step of hot extruding the composition at a hot melt temperature. |