http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107412731-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 |
| filingDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107412731-B |
| titleOfInvention | Application of UL43 protein in preparation of medicine for preventing and treating mitochondrial dysfunction |
| abstract | The invention discloses application of UL43 protein in preparing a medicament for preventing and treating cell mitochondrial dysfunction and preparing a medicament for preventing and treating metabolic syndrome. Experiments show that the UL43 protein can be endocytosed into cells from host cell membranes and positioned on mitochondria of host cells, and meanwhile, the UL43 protein can increase the activity of PFK-1 and PK enzymes in glycolysis pathways, generate a large amount of pyruvic acid to enter the mitochondria, and further activate TCA circulation and oxidative phosphorylation processes, so that the intracellular ATP content is increased, and the treatment of mitochondrial dysfunction and metabolic syndrome diseases is realized. |
| priorityDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 321.