http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107412280-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-04 |
| filingDate | 2016-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107412280-B |
| titleOfInvention | Nano-selenium hydrosol with anti-tumor activity, preparation and preservation method and application |
| abstract | The invention relates to the technical field of nano-selenium hydrosol, in particular to nano-selenium hydrosol with anti-tumor activity, and a preparation method, a preservation method and application thereof. The hydrosol at least comprises the following components in concentration: nano selenium of 0.5mmol/L to 5.0 mmol/L; the coriolus versicolor polysaccharide protein is 100.0 mg/L-600.0 mg/L. The preparation method of the hydrosol at least comprises the step S01, adding a solution containing selenium ions and/or selenious ions into the coriolus versicolor polysaccharide protein aqueous solution; s02, dropwise adding a reducing agent solution into the mixed solution obtained in the step S01, and oscillating; and S03, carrying out constant volume and dialysis treatment on the product obtained by the reduction reaction in the step S02. The hydrosol exists stably at the temperature of 2-10 ℃. Because the coriolus versicolor polysaccharide protein has hydrophilic hydroxyl and amino groups, the affinity of the nano selenium and cancer cells can be enhanced by the two groups, the intake of the nano selenium by the tumor cells is improved, the overall treatment effect of reducing the dosage, increasing the curative effect and reducing toxic and side effects is further achieved, and a more effective scheme is provided for clinical combined chemotherapy of cancer. |
| priorityDate | 2016-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.