http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107412195-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate | 2017-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107412195-B |
| titleOfInvention | PH-responsive antitumor drug carrier material and preparation and application thereof |
| abstract | The invention discloses a pH-responsive antitumor drug carrier material, and preparation and application thereof, wherein the preparation method comprises the following steps: (1) preparing mesoporous silica-coated gold nanoparticles, wherein the gold nanoparticles comprise gold nanospheres or gold nanorods; (2) preparing gold nanoparticles coated by carboxylated mesoporous silica; (3) preparing water-soluble zinc oxide quantum dots; (4) preparing the anti-tumor drug carrier material with pH response. By optimizing the whole process flow design of the preparation method and the parameter conditions adopted by each reaction step, the problems of uncontrollable drug release, low drug loading rate, easy side effect initiation and the like when the mesoporous silica coated gold nanoparticles are used as drug carriers can be effectively solved. |
| priorityDate | 2017-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.