http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107397959-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107397959-B |
| titleOfInvention | Preparation method and application of nano antagonist with ultrastructure on surface |
| abstract | The invention provides a preparation method and application of a nano antagonist with a surface having an ultrastructure, wherein the nano antagonist comprises a carrier module formed by a nano material, an ultrastructure module formed by a hydrophilic polymer and a temperature-sensitive polymer and a targeting module formed by polypeptide, the ultrastructure module is connected on the carrier module, and the targeting module is connected with the hydrophilic polymer of the ultrastructure module. The nano antagonist prepared by the invention can target to cell receptor protein through polypeptide ligand, effectively inhibit the downstream biological action mediated by the receptor, improve the in vivo stability and blood circulation time of the material through the ultrastructure, provide a new effective strategy for vascular imaging, disease treatment and the like, influence the biological function of organisms and further realize the disease treatment. |
| priorityDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.