| abstract |
The invention discloses N2, the new application of the disulfonic acid amide of N8 bis- (2 hydroxy phenyl) dibenzo [b, d] furans 2,8.Specifically, the N2, N8 bis- (2 hydroxy phenyl) dibenzo [b in the present invention, d] furans 2,8 disulfonic acid amides possess the function of AKR1B10 inhibitor, while have preferable inhibitory activity to AKR1B1, can be used for preparing the cancer therapy drug related to AKR1B10. |