http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107383151-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2017-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107383151-B |
| titleOfInvention | The Pentacyclic triterpene saponins compounds and its extracting method of anti-breast cancer activity in a kind of spina gleditsiae |
| abstract | The invention discloses the Pentacyclic triterpene saponins compounds and its extracting method of anti-breast cancer activity in a kind of spina gleditsiae, its extracting method includes the following steps: 1) will be after spina gleditsiae pulverizing medicinal materials, after organic extractant heating and refluxing extraction, concentration, spina gleditsiae crude extract is obtained；2) spina gleditsiae crude extract obtained in step 1) is dispersed in water, and is successively extracted with petroleum ether and ethyl acetate, obtained water phase, water phase position is obtained after water phase is concentrated；3) by absorption resin chromatography column absorption after being diluted with water obtained water phase position, ethanol-water system gradient elution is then used again, each elution fraction is concentrated to dryness；4) 60% alcohol-water elution fraction is used into CH after crossing silica gel column chromatography absorption 2 Cl 2 - MeOH system carries out gradient elution；5) by CH 2 Cl 2 - MeOH volume ratio is that the elution fraction of 1:1 crosses RP-C 18 After middle compression leg chromatography, gradient elution is carried out using methanol-water solution, 80% methanol-water is eluted into position CH 3 CN/H 2 Prepared by O (26:74, v/v), obtain spina gleditsiae saponin A. |
| priorityDate | 2017-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.