Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
filingDate |
2016-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-107382967-B |
titleOfInvention |
Carbazole sulfonamide derivative or pharmaceutically acceptable salt thereof, and preparation method and application thereof |
abstract |
The invention provides a carbazole sulfonamide derivative or a medicinal salt thereof, and a preparation method and application thereof. Wherein the carbazole sulfonamide derivative or the pharmaceutically acceptable salt thereof has the following general formula (1). The carbazole sulfonamide derivative or the medicinal salt thereof provided by the invention has an anti-microtubule effect and obvious anti-tumor activity as a micromolecular tubulin inhibitor, and meanwhile, the carbazole sulfonamide derivative or the medicinal salt thereof has small molecular weight, simple synthesis and small toxic and side effects. |
priorityDate |
2016-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |