http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107367539-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b75a05785dbfd86d27a87ddcdc5a524 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3277 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327 |
filingDate | 2017-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8654a8b3bb0bf7cedefc6395cae573e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62e4fe911014435abfb57b7eaa0f31b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b8d7d9c733ddcfe8adb2c7850d41781 |
publicationDate | 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107367539-A |
titleOfInvention | A kind of aptamer sensor and its construction method and application based on charge effect |
abstract | The invention discloses a kind of aptamer sensor based on charge effect and its construction method and application, the construction method of the sensor is that gold electrode is immersed in the tetrahydrofuran solution containing 4 [(trimethyl silicon substrate) acetenyl] benzoic acid and tetrabutyl ammonium fluoride, reacted in room temperature environment, obtain the gold electrode of 4 carboxyl phenyl acetenyls modification;Then DNA1 and DNA2 is subjected to hybridization reaction, obtains dsDNA;The gold electrode of 4 carboxyl phenyl acetenyls modification carries out acid amides reaction with dsDNA, then nanogold Streptavidin and sulfydryl ferrocene and the fit compound of tumor markers are added, produces that cost is low, stability is good, detection is simple, the aptamer sensor of high sensitivity, high specificity. |
priorityDate | 2017-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.