http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107365300-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12
filingDate 2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107365300-B
titleOfInvention A method of effectively removing impurity in Lansoprazole crude product
abstract The invention discloses a kind of methods for effectively removing impurity in Lansoprazole crude product.This method is to convert Lansoprazole crude product to after Lansoprazole salt to be dissolved in organic mixed solvent, is then evaporated under reduced pressure, and Lansoprazole precipitation is finally then converted to.Lansoprazole salt feature more higher than Lansoprazole stability is utilized in the method for the present invention, Lansoprazole purification yield can achieve 84.7% or more, and the impurity in Lansoprazole can be effectively removed, impurity A in highly finished product, impurity B, impurity C and impurity E content respectively in 0.011%, 0.013%, 0.012%0.015% hereinafter, and impurity D is then not detected.
priorityDate 2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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