http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107365278-A

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filingDate 2017-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40f6e748de832235a8eba59e39b062ea
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publicationDate 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107365278-A
titleOfInvention A kind of polysubstituted isoxazolidine derivative and its preparation method
abstract The invention relates to a multi-substituted isoxazolidine derivative and a preparation method thereof, the structural formula of which is shown in formula (I): Formula (I), wherein, R 1 and R 2 are substituted aryl or alkyl, and the substituent on Ar can be alkoxy, halogen or alkyl; the substituted aryl is phenyl or naphthyl, and the alkyl Usually include: methyl, ethyl, cyclohexyl, the preparation method steps are as follows: at room temperature, under air or nitrogen atmosphere, the nitrone derivative shown in formula (II), the nitrone derivative shown in formula (III) containing alkene structure The compound and the photocatalyst represented by formula (IV) are dissolved in an organic solvent, mixed uniformly, placed under a blue LEDs lamp or an incandescent lamp for several hours, and after the reaction is complete, the solvent is evaporated, and then separated by silica gel column chromatography Purification can obtain multi-substituted isoxazolidine derivatives; this method solves the problem that the existing synthesis of isoxazolidine derivatives requires a high-temperature heating system, high energy consumption, harsh conditions, and great requirements for equipment. The conditions are mild, the method is simple and The operation is convenient and the productivity is high.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107746392-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109796422-A
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107746392-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112939883-A
priorityDate 2017-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 30.