| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74ca034abd5ce84d1c39ff9a5b6f915f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2387-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L87-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00 |
| filingDate |
2016-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae1b28271dad78aaeddb8be8641af7f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_223e3534ac4f3cffd9cbf0e1768c0c98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4b4d712125bc93a4ac59b9d1af979e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1c086bb89e0137f9f3a3a090637650d |
| publicationDate |
2017-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-107344971-A |
| titleOfInvention |
A kind of poly-ε-lysine modified chitosan and its preparation method |
| abstract |
The invention discloses a poly-ε-lysine modified chitosan and a preparation method thereof. The preparation method comprises the following steps: 1) dissolving the chitosan into an MES buffer solution with a pH of 4.5-5.0 to form a shell Glycan solution; dissolve poly‑ε‑lysine, N‑hydroxysuccinimide and 1‑(3‑dimethylaminopropyl)‑3‑ethylcarbodiimide hydrochloride in 2‑(N -morpholino) ethanesulfonic acid (MES) buffer solution, obtain poly-ε-lysine activation solution; 2) poly-ε-lysine activation solution is added in chitosan solution, at 0～35 Reaction at ℃ for 6 to 48 hours; 3) adding hydroxylamine hydrochloride to the reaction solution in step 2) to terminate the reaction; 4) filtering the reaction solution, and then dialysis with water to obtain a poly-ε-lysine modified chitosan solution; 5 ) and dry to obtain poly-ε-lysine modified chitosan. The poly‑ε‑lysine modified chitosan has good antibacterial properties and high biological safety. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109053928-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112717209-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114478836-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115572397-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112717209-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115572397-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113896812-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113896812-A |
| priorityDate |
2016-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |