http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107343880-B

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filingDate 2017-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107343880-B
titleOfInvention Warfarin sodium orally disintegrating tablet capable of being individually administrated and prepared by 3D printing and preparation method thereof
abstract The invention discloses a warfarin sodium orally disintegrating tablet capable of being individually administrated and prepared by 3D printing, which is mainly prepared from the following components in percentage by mass by adopting a 3D printing technology: 1-10% of warfarin sodium, 90-99% of filler, 0.1-1.0% of superfine silica powder and 0-2% of flavoring agent, wherein the sum of the mass percentages of the components is equal to 100%. The invention also discloses a preparation method of the warfarin sodium orally disintegrating tablet. The warfarin sodium orally disintegrating tablet provided by the invention has the advantages that the drug release speed is high, the content of the tablet is determined by taking the number of printing layers as a variable under the condition that the prescription and the process parameters are the same, namely, the dosage of the tablet can be individually designed by changing the number of printing layers, the dosage suitable for a patient can be customized according to the individual difference of the patient, the individual administration and the precise treatment are realized, the number of tablets taken by the patient is reduced or the steps of cutting the tablet by a pharmacist are reduced, the medicinal preparation can exert the maximum curative effect, and the toxic and side effects of the medicine are reduced to the minimum.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023280816-A1
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