| abstract |
The present application discloses a preparation method of compound I, which is characterized in that compound I is prepared by reacting ketone compound II and chlorinated organic phosphine compound III in the presence of oxygen-containing compounds. Compared with the existing synthesis method of preparing DiDOPO from DOPO and aryl alkyl ketone under the catalysis of phosphorus oxychloride, the method shortens the reaction steps, effectively reduces the cost, and improves the operability and safety of the process. properties, the purification of the product is easier and the yield is higher. |