http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107325028-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-30 |
| filingDate | 2017-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107325028-B |
| titleOfInvention | Fulvestrant side chain intermediate synthetic method |
| abstract | The present invention relates to a kind of preparation methods of fulvestrant side chain intermediate, specifically Pentafluorobenzyl pentanol is reacted with the p-methyl benzenesulfonic acid of load over a molecular sieve is made Pentafluorobenzyl pentanol p-methyl benzenesulfonic acid ester, Pentafluorobenzyl pentanol p-methyl benzenesulfonic acid ester is reacted with thiocarbamide in ethanol is made 4,4,5,5,5- five fluorine amyl group isothiourea mesylates.The invention avoids acyl chlorides is used, production technology is optimized, improves reaction yield, reduces environmental pollution. |
| priorityDate | 2017-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.