| abstract |
The present invention relates to a kind of β trifluoromethyls enamine derivates, its general structure is as follows： Wherein, R 1 、R 2 、R 3 、R 4 、R 5 、R 6 、R 7 、R 8 、R 9 、R 10 Independently selected from hydrogen, alkyl, alkoxy, halogen or trifluoromethyl.Present invention also offers a kind of preparation method of above-mentioned β trifluoromethyls enamine derivates, comprise the following steps：N (vinyl of 2 phenyl 1) heterocyclic carbamate derivatives and tongi reagents will be replaced, in organic solvent in being reacted at 80 100 DEG C, to obtain β trifluoromethyl enamine derivates in the presence of alkali, part and copper salt catalyst.The present invention method can be in high yield obtain a variety of β trifluoromethyls enamine derivates；Reaction condition is gentle, operation and last handling process are simple, is suitable for large-scale production. |