http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107324399-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01G49-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01G49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 |
| filingDate | 2017-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107324399-B |
| titleOfInvention | A kind of iron oxide nano material and the purposes as tumour medicine targeting carrier |
| abstract | The purposes of carrier is targeted the invention discloses a kind of iron oxide nano material and as tumour medicine, the iron oxide nano material is prepared via a method which: first iron chloride, polyvinylpyrrolidone and double-(3- methyl-1-imidazoles) butylidenebis disulfate being dissolved in distilled water, hydro-thermal reaction is carried out again, reaction temperature is 180-220 DEG C, reaction time is 18-22h, is finally centrifuged, washs, is dry, calcining, grinding；Wherein, the molar concentration of iron chloride is 0.03-0.04mol/L, and the concentration of polyvinylpyrrolidone is 8-12g/L, the molar concentration 0.01-0.02mol/L of double-(3- methyl-1-imidazoles) butylidenebis disulfate.Iron oxide nano material provided by the invention has the affinity of specificity to leukemia tumor cells, and may be used as the pharmaceutical carrier of selectively targeted leukemia tumor cells without obvious affinity interaction to tumour cells such as gastric cancer, lung cancer；Moreover, the iron oxide nano material to normal cell without obvious cytotoxicity, it is highly-safe. |
| priorityDate | 2017-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.