http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107320440-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0065 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
filingDate | 2017-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107320440-B |
titleOfInvention | Sulforaphane-containing gastric retention composition and preparation method thereof |
abstract | The invention relates to a sulforaphane composition preparation, in particular to a sulforaphane gastric retention composition, and belongs to the technical field of medicinal preparations. The gastric retention composition comprises 1-100 parts by weight of a pharmacodynamic ingredient sulforaphane, and the pharmaceutic adjuvant comprises the following components in parts by weight: 15-100 parts of hydrophilic gel skeleton, 10-200 parts of bleaching aid and/or adhesive, 10-100 parts of swelling agent, 10-100 parts of regulator and 0-50 parts of glidant. The gastric retention composition can prolong the retention time in the stomach and play a role in slowly releasing the sulforaphane, thereby reducing the decomposition of the sulforaphane, maintaining the effective treatment concentration and action time of the sulforaphane at a target position and improving the bioavailability and the drug effect. The preparation method skillfully avoids the degradation of the sulforaphane product and the components in the production process, improves the controllability of the product quality process, and is suitable for industrial production. |
priorityDate | 2017-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.