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filingDate 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107308505-B
titleOfInvention Sodium alginate-modified gelatin-modified dopamine composite scaffold and preparation method thereof
abstract The invention discloses a sodium alginate-modified gelatin-modified dopamine composite stent and a preparation method thereof. The preparation method comprises double-bonding modification of gelatin and dopamine, preparation of three-dimensional printing slurry and three-dimensional printing forming of the tissue engineering scaffold. According to the invention, a small amount of calcium ions are pre-crosslinked to obtain the slurry which is similar to the inorganic powder with high solid content and is beneficial to printing and forming, the prepared bracket can maintain the three-dimensional porous structure, the preparation of the printing slurry is optimized, excessive auxiliary conditions are not needed for printing, and the material is greatly saved. The preparation method of the composite scaffold has the advantages of mild conditions, simple method and easy realization. The prepared composite scaffold can be used in the fields of skin repair, drug sustained release, tissue engineering and the like.
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