http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107287256-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12 |
| filingDate | 2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107287256-B |
| titleOfInvention | Method for synthesizing L-2-piperidinecarboxylic acid by whole-cell catalysis |
| abstract | The invention belongs to the technical field of biocatalysis, and particularly relates to a method for synthesizing L-2-piperidinecarboxylic acid by whole-cell catalysis. The method for synthesizing the L-2-piperidinecarboxylic acid by whole-cell biocatalysis disclosed by the invention is characterized in that L-lysine hydrochloride is used as a substrate, and L-2-piperidinecarboxylic acid is prepared by biocatalysis by adding nicotinamide adenine dinucleotide and a recombinant host bacterium containing an Arenimonas donghaensis DSM 18148 protein encoding gene, or a recombinant host bacterium containing a Pseudomonas veronii CIP104663 protein encoding gene or a recombinant host bacterium containing a Streptomyces hirsutus ATCC 19091 protein encoding gene. Thereby overcoming the problems of high cost, rigorous conditions, low conversion rate, high energy consumption and large pollution of the existing chemical synthesis method. Meanwhile, the biological catalysis system disclosed by the invention has the advantages of high enzyme activity efficiency, short reaction time and high ee value of the target product. |
| priorityDate | 2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 417.