http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107286203-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F17-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F17-02 |
| filingDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107286203-B |
| titleOfInvention | Preparation method and application of chiral Ugi's amine and derivatives and optical isomers thereof |
| abstract | The invention discloses a method for synthesizing Ugi's amine shown in formula (I) and derivatives and optical isomers thereof, which takes chiral amine shown in formula (VI) and ferrocene shown in formula (V) as initial raw materials, and obtains the chiral Ugi's amine shown in formula (I) and derivatives and optical isomers thereof through reductive amination, reductive amination or amino alkylation, substitution reaction and amine substitution reaction in sequence; or through reductive amination, hydrogenation debenzylation, reductive amination or amine alkylation reaction to obtain chiral Ugi's amine of the formula (I) and derivatives and optical isomers thereof. The chiral Ugi's amine of the formula (I) and derivatives and optical isomers thereof can be used for synthesizing Josiphos ferrocene diphosphine ligands, are used as chiral ligands of various metal complex catalysts, are important chiral catalyst ligands for preparing medical intermediates and agricultural chemicals, have wide application in metal-catalyzed asymmetric reactions, and are suitable for industrial scale production. |
| priorityDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.