abstract |
The invention discloses a dinuclear aryl ruthenium metal complex, and also discloses a synthesis method of the above dinuclear aryl ruthenium metal complex: dissolving a certain amount of aryl ruthenium dimer in an organic solvent under an inert gas atmosphere , to obtain the initial solution; 1,3-bis(1H-imidazol-1-yl)benzene 1,3-bib ligand is added to the initial solution, and reacted for a period of time at a certain temperature to obtain a mixed solution; to the mixed solution Add the required anion salt, stir at room temperature for a period of time, then filter, concentrate the filtrate, and further purify the crude product by column chromatography to obtain a dinuclear aryl ruthenium metal complex. The preparation method of the present invention has simple technological process, easy operation, and high product yield; the prepared dinuclear aryl ruthenium metal complex has good anticancer activity, can be applied to the preparation of anticancer drugs or anticancer drug components, and has good Pharmaceutical application prospects. |