| abstract |
The invention relates to cefoperazone sodium tazobactam sodium for injection and a preparation process thereof. The invention adopts the stabilizing agent consisting of sodium pyrosulfite and glycine, Tween 80 and cholesterol as emulsifying agents, sodium deoxycholate as co-emulsifying agents and trehalose as freeze-drying supporting agents, effectively improves the stability of cefoperazone sodium and tazobactam sodium in the preparation and storage processes, has quick dissolution of the preparation, does not generate crystallization and turbidity phenomena, and ensures the curative effect and safety of clinical use. |