| abstract |
The present invention discloses a kind of detection model of Sera of Lung Cancer gene, and the detection model is made up of 5 polypeptides, and the m/z that MALDI TOF MS analyses are obtained is respectively 4092.4Da, 4585.05Da, 1365.1Da, 4643.49Da and 4438.43Da.The invention also discloses the construction method of above-mentioned detection model.The detection model of Sera of Lung Cancer gene of the present invention, which carries out EGFR genetic mutation state estimation, only needs 5 microlitres of serum, and low-cost, rapidly, and this method can be achieved to be automatically brought into operation substantially.In addition, detection model susceptibility of the present invention can reach tissue ARMS genetic test susceptibilitys, the accuracy of detection is substantially increased. |