http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107266585-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K20-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K20-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate | 2017-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107266585-B |
titleOfInvention | A kind of MLH fusion antibacterial peptide and its preparation method and application |
abstract | The invention discloses a kind of MLH fusion antibacterial peptides and its preparation method and application, using house fly antibiotic peptide, LL-37 and helicobacter pylori peptide as parent peptide, the amino acid sequence for obtaining MLH is analyzed using bioinformatics method, and according to the genetic fragment of E.coli codon preference encoding hybrid gene M LH.Using target gene needed for the synthesis of SOE-PCR technology, and it is connect with expression vector pET-32a (+), conversion to E. coli expression strains construct recombination engineering bacteria pET-32a-MLH/BL21 (DE3), through IPTG inducible protein amalgamation and expression, bacteriostatic activity identification finally is carried out to the hybrid peptide of the amalgamation and expression of acquisition, the result shows that the hybrid peptide of amalgamation and expression has apparent fungistatic effect to staphylococcus aureus and bacillus subtilis. |
priorityDate | 2017-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.