http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107266578-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55594 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 |
| filingDate | 2016-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107266578-B |
| titleOfInvention | Oral vaccine for clonorchiasis sinensis and preparation and application thereof |
| abstract | The invention belongs to the technical field of biology, and particularly relates to an oral vaccine for clonorchiasis sinensis of fish, and preparation and application thereof. The invention firstly provides a fusion protein which contains bacillus subtilis spore capsid protein CotC and clonorchis sinensis cysteine protease Cs And (6) CP. The fusion protein is prepared into the oral vaccine for the clonorchiasis sinensis by taking bacillus subtilis spores as a carrier, can be successfully planted in intestinal tracts of fish bodies, and has a good immune effect. Can cut off the spreading way of clonorchiasis sinensis and achieve the purpose of effectively preventing and controlling the epidemic and spreading of the clonorchiasis sinensis. The bacillus subtilis is selected as a protein antigen presentation system, so that the defect that the direct oral administration of pure protein is easy to degrade in a fish body gastric acid environment can be well overcome, and the vaccine can be ensured to play an effective protection role. |
| priorityDate | 2016-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 232.