http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107254514-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
| filingDate | 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107254514-B |
| titleOfInvention | SNP molecular marker for detecting heterologous cfDNA, detection method and application |
| abstract | The invention discloses an SNP molecular marker for detecting heterologous cfDNA, a detection probe and a chip designed based on the SNP molecular marker, and a detection device, a kit and a detection method for the heterologous cfDNA; the detection chip and the detection device are used for quantifying the allogenic cfDNA in the receptor after the kidney transplantation, so that a basis is provided for detecting the rejection reaction of the kidney transplantation, the noninvasive early detection with high sensitivity and high specificity for the kidney transplantation is realized, and the continuous monitoring can be carried out on the kidney transplantation patient; the SNP molecular marker comprises SNP loci of drug metabolism genes, provides mutation information of drug genes for patients with kidney transplantation rejection, and realizes individualized drug administration; the invention also provides a single molecular marker joint which is used for constructing a sequencing library to effectively remove repeated data and errors randomly introduced in the sequencing and PCR processes, reduces the background noise of sequencing and improves the accuracy of detection. |
| priorityDate | 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.