http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107238661-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2291-014 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N29-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N29-12 |
filingDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107238661-B |
titleOfInvention | A kind of cell tractive force and viscoelastic Simultaneous Determination method |
abstract | The invention discloses a kind of cell tractive force and viscoelastic Simultaneous Determination method.The method is AT is cut quartz crystal and BT to cut quartz crystal to be placed in culture dish or detection cell, and the AT, which cuts quartz crystal and BT and cuts quartz crystal, to be had identical frequency, configuration of surface and/or modified identical surface adhesion molecule;Cell to be measured is added into culture dish or detection cell, cell tractive force Δ S is determined by equation below (I):Δ S=(K AT ‑K BT ) ‑l [t q AT Δf AT /fr AT ‑tq BT Δf BT /fr BT ] (I), cell viscoplasticity is by equation below (II) and (III) quantitatively and/or by public formula (IV) sxemiquantitative characterization.Cell storage modulus G '=π 2 Z q 2 (ΔR 2 /16π 2 L q 2 ‑Δf 2 )/ρ liq f r 2 (II), cell depletion modulus G "=π Z q 2 ΔfΔR/2L q ρ liq f r 2 (III), cell viscoelastic index CVI=Δs R/ Δs f (IV).The present invention can be used for research cell to be in the lower cell power of different internal and external environments excitation and viscoelastic dynamic rule, and such as the influence of medicine, medicine can be added before cell adhesion or after sticking.The present invention is suitable for all attached cells, including primary cell and passage cell. |
priorityDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.