http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107235842-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-11 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107235842-B |
| titleOfInvention | Phenylpropanoate derivative and preparation method and application thereof |
| abstract | The invention discloses a phenylpropionate derivative, a preparation method and an application thereof, wherein the structure of the phenylpropionate derivative is shown as a formula I: wherein R is 1 、R 2 Is H, OH, OCH 3 Isopentenyl, 3-methylbut-2-enyl, alkyl; r 3 Is H, CH 3 、i‑Pr、t‑Bu、CF 3 Or OCH 3 . The rat diabetes model induced by the OGTT and STZ of a normal mouse shows that the derivative has obvious hypoglycemic activity, can reduce the blood sugar of a rat of the diabetes model in a dose-dependent manner, has a certain protection effect on a mouse with high-fat diabetes, proves the hypoglycemic effect and the lipid-lowering effect of the derivative, and can be used for preparing related medicaments for the adjuvant therapy of diabetes, particularly obesity-type diabetes and diabetic complications. |
| priorityDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.