| abstract |
The invention discloses a three-dimensional printing porous whitlockite biological ceramic scaffold and a preparation method and application thereof. The method comprises the steps of firstly blending the whitlockite powder, the sintering aid and a certain proportion of a binder aqueous solution to obtain slurry, then preparing a ceramic support blank with a controllable porous structure by using a three-dimensional printing technology, and then sintering at high temperature to obtain the whitlockite ceramic support material with the porous structure and good mechanical properties. The three-dimensional printed whitlockite biological ceramic scaffold prepared by the invention has controllable aperture and porosity, good biocompatibility, and remarkably better mechanical property than a calcium phosphate ceramic scaffold with the same structure, and simultaneously has excellent induced osteogenesis activity and angiogenesis activity, and is expected to be used for promoting the regeneration and repair of various types of defective bone tissues. |