http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107226846-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 |
| filingDate | 2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107226846-B |
| titleOfInvention | Novel hyaluronic acid binding peptide and transdermal absorption and subcutaneous targeted release preparation |
| abstract | The invention relates to a novel hyaluronic acid binding peptide and a transdermal absorption and subcutaneous targeted release preparation, wherein HaBP capable of being specifically bound with hyaluronic acid is designed, the HaBP is incubated and mixed with cell penetrating peptide and HA under certain conditions, and three parts of the HaBP, the cell penetrating peptide and a subcutaneous endogenous protease enzyme cutting site are connected together to construct fusion protein and then incubated with the HA, so that transmembrane transport and transdermal absorption of hyaluronic acid can be remarkably promoted, and subcutaneous targeted release of the HA is realized. The method overcomes the defect of low transdermal absorptivity of hyaluronic acid as a biological macromolecular substance, enables the hyaluronic acid to efficiently cross over the stratum corneum of the skin, and plays a role in promoting cell proliferation in subcutaneous targeted release so as to play the actual effects of the hyaluronic acid in the aspects of skin care, moisture preservation, wrinkle removal, whitening and the like, and provides a new thought and a new method for the development and production of related beauty products and biological medicines. |
| priorityDate | 2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.