http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107226783-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2017-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107226783-B |
titleOfInvention | A kind of lysosome targeting fluorescent probe and preparation method thereof |
abstract | The invention discloses a kind of lysosome targeting fluorescent probes and preparation method thereof, with α, alpha, beta-unsaturated ketone is the big pi-conjugated system that receptor constructs D- π-A- π-D (donor-pi-acceptor-π-donor) type, it is acted on by Intramolecular electron transfer, the excitation wavelength of molecule can be made to compare many fluorescence probe greatly red shifts for being used for lysosome at present with launch wavelength, so that the interference of background signal be effectively reduced.Compound provided by the invention is used for the fluorescence imaging of lysosome, in cellular environment, red fluorescence can be emitted in acid condition, maximum emission wavelength can be realized the targeting label to lysosome up to 625nm or so, background interference is small, and method is sensitive, simple, quick. |
priorityDate | 2017-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.